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A Conserved 20S Proteasome Assembly Factor Requires a C-terminal HbYX Motif for Proteasomal Precursor Binding

Dedicated chaperones facilitate eukaryotic proteasome assembly, yet how they function remains largely unknown. Here we demonstrate that a yeast 20S proteasome assembly factor, Pba1–Pba2, requires a previously overlooked C-terminal HbYX (hydrophobic-tyrosine-X) motif for function. HbYX motifs in prot...

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Detalles Bibliográficos
Autores principales: Kusmierczyk, Andrew R., Kunjappu, Mary J., Kim, Roger Y., Hochstrasser, Mark
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087856/
https://www.ncbi.nlm.nih.gov/pubmed/21499243
http://dx.doi.org/10.1038/nsmb.2027