Cargando…
A Conserved 20S Proteasome Assembly Factor Requires a C-terminal HbYX Motif for Proteasomal Precursor Binding
Dedicated chaperones facilitate eukaryotic proteasome assembly, yet how they function remains largely unknown. Here we demonstrate that a yeast 20S proteasome assembly factor, Pba1–Pba2, requires a previously overlooked C-terminal HbYX (hydrophobic-tyrosine-X) motif for function. HbYX motifs in prot...
Autores principales: | Kusmierczyk, Andrew R., Kunjappu, Mary J., Kim, Roger Y., Hochstrasser, Mark |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087856/ https://www.ncbi.nlm.nih.gov/pubmed/21499243 http://dx.doi.org/10.1038/nsmb.2027 |
Ejemplares similares
-
Minimal mechanistic component of HbYX-dependent proteasome activation
por: Chuah, Janelle J., et al.
Publicado: (2023) -
Minimal mechanistic component of HbYX-dependent proteasome activation that reverses impairment by neurodegenerative-associated oligomers
por: Chuah, Janelle J. Y., et al.
Publicado: (2023) -
Alpha-ring Independent Assembly of the 20S Proteasome
por: Panfair, Dilrajkaur, et al.
Publicado: (2015) -
AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation
por: Li, Jianhui, et al.
Publicado: (2019) -
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome
por: Huber, Eva M., et al.
Publicado: (2016)