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Non-invasive Optical Imaging of Muscle Pathology in mdx Mice Using Cathepsin Caged Near-Infrared Imaging

PURPOSE: To develop a reliable live-animal imaging method for monitoring muscle pathology in mouse models of myopathy. PROCEDURES: A caged near-infrared Cathepsin B (CTSB) substrate, ProSense 680, is evaluated in the dystrophin deficient mdx mice, a genetic homologue of Duchenne muscular dystrophy v...

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Detalles Bibliográficos
Autores principales:	Baudy, Andreas R., Sali, Arpana, Jordan, Sarah, Kesari, Akanchha, Johnston, Helen K., Hoffman, Eric P., Nagaraju, Kanneboyina
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087873/ https://www.ncbi.nlm.nih.gov/pubmed/20661652 http://dx.doi.org/10.1007/s11307-010-0376-z

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