Cargando…
Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model
Rhabdomyosarcoma is an aggressive childhood malignancy, accounting for more than 50% of all soft-tissue sarcomas in children. Even with extensive therapy, the survival rate among alveolar rhabdomyosarcoma patients with advanced disease is only 20%. The receptor tyrosine kinase Epidermal Growth Facto...
Autores principales: | Abraham, Jinu, Nelon, Laura D., Kubicek, Courtney B., Kilcoyne, Aoife, Hampton, Sheila T., Zarzabal, Lee Ann, Giles, Francis J., Michalek, Joel E., Rubin, Brian P., Keller, Charles |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087964/ https://www.ncbi.nlm.nih.gov/pubmed/21559212 http://dx.doi.org/10.1155/2011/130484 |
Ejemplares similares
-
Protein Kinase C iota as a Therapeutic Target in Alveolar Rhabdomyosarcoma
por: Kikuchi, Ken, et al.
Publicado: (2012) -
Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma
por: Kikuchi, Ken, et al.
Publicado: (2013) -
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma
por: Bharathy, Narendra, et al.
Publicado: (2019) -
The Case for Primary Salivary Rhabdomyosarcoma
por: Geltzeiler, Mathew, et al.
Publicado: (2015) -
Lineage of origin in rhabdomyosarcoma informs pharmacological response
por: Abraham, Jinu, et al.
Publicado: (2014)