Right Ventricular Dysfunction and Failure in Chronic Pressure Overload

Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse t...

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Detalles Bibliográficos
Autores principales: Simon, Marc A., Pinsky, Michael R.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087982/
https://www.ncbi.nlm.nih.gov/pubmed/21559218
http://dx.doi.org/10.4061/2011/568095
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author Simon, Marc A.
Pinsky, Michael R.
author_facet Simon, Marc A.
Pinsky, Michael R.
author_sort Simon, Marc A.
collection PubMed
description Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse the remodeling process are likely to improve outcomes. We review the current understanding of RV dysfunction in chronic pressure overload and introduce some novel insights based on recent investigations into pathophysiology, diagnosis, and treatment.
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spelling pubmed-30879822011-05-10 Right Ventricular Dysfunction and Failure in Chronic Pressure Overload Simon, Marc A. Pinsky, Michael R. Cardiol Res Pract Review Article Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse the remodeling process are likely to improve outcomes. We review the current understanding of RV dysfunction in chronic pressure overload and introduce some novel insights based on recent investigations into pathophysiology, diagnosis, and treatment. SAGE-Hindawi Access to Research 2011-03-23 /pmc/articles/PMC3087982/ /pubmed/21559218 http://dx.doi.org/10.4061/2011/568095 Text en Copyright © 2011 M. A. Simon and M. R. Pinsky. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Simon, Marc A.
Pinsky, Michael R.
Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title_full Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title_fullStr Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title_full_unstemmed Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title_short Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
title_sort right ventricular dysfunction and failure in chronic pressure overload
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087982/
https://www.ncbi.nlm.nih.gov/pubmed/21559218
http://dx.doi.org/10.4061/2011/568095
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AT pinskymichaelr rightventriculardysfunctionandfailureinchronicpressureoverload

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