Ovarian Germline Stem Cells in the Teleost Fish, Medaka (Oryzias latipes)

In the mammalian testis germline stem cells keep producing many sperms, while there is no direct evidence for the presence of germline stem cells in the ovary. It is widely accepted in mammals that the mature oocytes are supplied from a pool of primordial follicles in the adult ovary. In other verte...

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Detalles Bibliográficos
Autores principales: Nakamura, Shuhei, Kobayashi, Kayo, Nishimura, Toshiya, Tanaka, Minoru
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088282/
https://www.ncbi.nlm.nih.gov/pubmed/21547057
Descripción
Sumario:In the mammalian testis germline stem cells keep producing many sperms, while there is no direct evidence for the presence of germline stem cells in the ovary. It is widely accepted in mammals that the mature oocytes are supplied from a pool of primordial follicles in the adult ovary. In other vertebrates, such as fish, however, there has been no investigation on the mechanism underlying the high egg-producing ability. In this review, we introduce the recently identified ovarian germline stem cells and the surrounding unique structure in teleost fish, medaka (Oryzias latipes) [Nakamura S et al. Science. 2010; 328: 1561-1563]. We also discuss about the expression and function of sox9 that characterizes this unique structure.

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