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Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors
The cancer stem cell (CSC) concept is a highly debated topic in cancer research. While experimental evidence in favor of the cancer stem cell theory is apparently abundant, the results are often criticized as being difficult to interpret. An important reason for this is that most experimental data t...
Autores principales: | Sottoriva, Andrea, Vermeulen, Louis, Tavaré, Simon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088646/ https://www.ncbi.nlm.nih.gov/pubmed/21573198 http://dx.doi.org/10.1371/journal.pcbi.1001132 |
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