Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens

Treatment of EGFR-mutant non-small cell lung cancer patients with the tyrosine kinase inhibitors erlotinib or gefitinib results in high response rates and prolonged progression-free survival. Despite the development of sensitive mutation detection approaches, a thorough validation of these in a clin...

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Detalles Bibliográficos
Autores principales: Querings, Silvia, Altmüller, Janine, Ansén, Sascha, Zander, Thomas, Seidel, Danila, Gabler, Franziska, Peifer, Martin, Markert, Eva, Stemshorn, Kathryn, Timmermann, Bernd, Saal, Beate, Klose, Stefan, Ernestus, Karen, Scheffler, Matthias, Engel-Riedel, Walburga, Stoelben, Erich, Brambilla, Elisabeth, Wolf, Jürgen, Nürnberg, Peter, Thomas, Roman K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088700/
https://www.ncbi.nlm.nih.gov/pubmed/21573178
http://dx.doi.org/10.1371/journal.pone.0019601

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