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Serum Response Factor Controls CYLD Expression via MAPK Signaling Pathway
Tumor suppressor gene CYLD is a deubiquitinating enzyme which negatively regulates various signaling pathways by removing the lysine 63-linked polyubiquitin chains from several specific substrates. Loss of CYLD in different types of tumors leads to either cell survival or proliferation. In this stud...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088714/ https://www.ncbi.nlm.nih.gov/pubmed/21573132 http://dx.doi.org/10.1371/journal.pone.0019613 |