Cargando…

Serum Response Factor Controls CYLD Expression via MAPK Signaling Pathway

Tumor suppressor gene CYLD is a deubiquitinating enzyme which negatively regulates various signaling pathways by removing the lysine 63-linked polyubiquitin chains from several specific substrates. Loss of CYLD in different types of tumors leads to either cell survival or proliferation. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Gang, Ahlqvist, Kristofer, Pannem, Rajeswararao, Posern, Guido, Massoumi, Ramin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088714/
https://www.ncbi.nlm.nih.gov/pubmed/21573132
http://dx.doi.org/10.1371/journal.pone.0019613