Suppression of Lung Adenocarcinoma Progression by Nkx2-1

Despite the high prevalence and poor outcome of patients with metastatic lung cancer, the mechanisms of tumour progression and metastasis remain largely uncharacterized. We modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS1 and inactivation of the p53-p...

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Detalles Bibliográficos
Autores principales: Winslow, Monte M., Dayton, Talya L., Verhaak, Roel G. W., Kim-Kiselak, Caroline, Snyder, Eric L., Feldser, David M., Hubbard, Diana D., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie, Crowley, Denise, Bronson, Roderick T., Chiang, Derek Y., Meyerson, Matthew, Jacks, Tyler
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088778/
https://www.ncbi.nlm.nih.gov/pubmed/21471965
http://dx.doi.org/10.1038/nature09881

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