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CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE

Congenital cutaneous candidiasis (CCC) is an extremely rare disorder that presents within the first 6 days of life. The manifestations ranges from diffuse skin eruption without any systemic symptoms to respiratory distress, hepatosplenomegaly, sepsis, and death. We report a neonate who presented wit...

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Autores principales: Jagtap, Sujit A, Saple, Pallavi P, Dhaliat, Saleha B
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088947/
https://www.ncbi.nlm.nih.gov/pubmed/21572803
http://dx.doi.org/10.4103/0019-5154.77564
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author Jagtap, Sujit A
Saple, Pallavi P
Dhaliat, Saleha B
author_facet Jagtap, Sujit A
Saple, Pallavi P
Dhaliat, Saleha B
author_sort Jagtap, Sujit A
collection PubMed
description Congenital cutaneous candidiasis (CCC) is an extremely rare disorder that presents within the first 6 days of life. The manifestations ranges from diffuse skin eruption without any systemic symptoms to respiratory distress, hepatosplenomegaly, sepsis, and death. We report a neonate who presented with generalized skin eruptions at birth, characterized by erythematous macules and papules. The eruption involved head, face, neck, trunk, and extremities. Candida albicans was demonstrated on direct KOH smear, skin biopsy. The disease implies a congenital intrauterine infection and is different from neonatal candidiasis, which manifests as thrush or diaper dermatitis. The infection is acquired from the maternal genital tract in an ascending fashion. Clinical features, direct smear examination of specimen, and appropriate cultures are useful in differentiating the lesions from other more common dermatoses of the neonatal period. Topical antifungal therapy is sufficient unless systemic candidiasis is present. Prognosis for congenital cutaneous candidiasis is good.
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spelling pubmed-30889472011-05-13 CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE Jagtap, Sujit A Saple, Pallavi P Dhaliat, Saleha B Indian J Dermatol Case Report Congenital cutaneous candidiasis (CCC) is an extremely rare disorder that presents within the first 6 days of life. The manifestations ranges from diffuse skin eruption without any systemic symptoms to respiratory distress, hepatosplenomegaly, sepsis, and death. We report a neonate who presented with generalized skin eruptions at birth, characterized by erythematous macules and papules. The eruption involved head, face, neck, trunk, and extremities. Candida albicans was demonstrated on direct KOH smear, skin biopsy. The disease implies a congenital intrauterine infection and is different from neonatal candidiasis, which manifests as thrush or diaper dermatitis. The infection is acquired from the maternal genital tract in an ascending fashion. Clinical features, direct smear examination of specimen, and appropriate cultures are useful in differentiating the lesions from other more common dermatoses of the neonatal period. Topical antifungal therapy is sufficient unless systemic candidiasis is present. Prognosis for congenital cutaneous candidiasis is good. Medknow Publications 2011 /pmc/articles/PMC3088947/ /pubmed/21572803 http://dx.doi.org/10.4103/0019-5154.77564 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jagtap, Sujit A
Saple, Pallavi P
Dhaliat, Saleha B
CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title_full CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title_fullStr CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title_full_unstemmed CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title_short CONGENITAL CUTANEOUS CANDIDIASIS: A RARE AND UNPREDICTABLE DISEASE
title_sort congenital cutaneous candidiasis: a rare and unpredictable disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088947/
https://www.ncbi.nlm.nih.gov/pubmed/21572803
http://dx.doi.org/10.4103/0019-5154.77564
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