The role of C-terminus carbohydrate-binding domain of Vibrio cholerae haemolysin/cytolysin in the conversion of the pre-pore β-barrel oligomer to a functional diffusion channel

BACKGROUND & OBJECTIVES: Vibrio cholerae cytolysin/hemolysin (VCC) is a 65 kDa pore-forming toxin (PFT) secreted by O1 El Tor and non-O1 strains. The purified toxin, which contains two C-terminus carbohydrate-binding domains in addition to the cytolytic domain at the core, causes lysis of a wide...

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Detalles Bibliográficos
Autores principales: Mazumdar, Budhaditya, Ganguly, Sreerupa, Ghosh, Amar N., Banerjee, Kalyan K.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089043/
https://www.ncbi.nlm.nih.gov/pubmed/21415486

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