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Molecular mechanism of acquisition of the cholera toxin genes

One of the major pathogenic determinants of Vibrio cholerae, the cholera toxin, is encoded in the genome of a filamentous phage, CTXφ. CTXφ makes use of the chromosome dimer resolution system of V. cholerae to integrate its single stranded genome into one, the other, or both V. cholerae chromosomes....

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Detalles Bibliográficos
Autores principales: Das, Bhabatosh, Bischerour, Julien, Barre, François-Xavier
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089051/
https://www.ncbi.nlm.nih.gov/pubmed/21415494
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author Das, Bhabatosh
Bischerour, Julien
Barre, François-Xavier
author_facet Das, Bhabatosh
Bischerour, Julien
Barre, François-Xavier
author_sort Das, Bhabatosh
collection PubMed
description One of the major pathogenic determinants of Vibrio cholerae, the cholera toxin, is encoded in the genome of a filamentous phage, CTXφ. CTXφ makes use of the chromosome dimer resolution system of V. cholerae to integrate its single stranded genome into one, the other, or both V. cholerae chromosomes. Here, we review current knowledge about this smart integration process.
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spelling pubmed-30890512011-05-16 Molecular mechanism of acquisition of the cholera toxin genes Das, Bhabatosh Bischerour, Julien Barre, François-Xavier Indian J Med Res Review Article One of the major pathogenic determinants of Vibrio cholerae, the cholera toxin, is encoded in the genome of a filamentous phage, CTXφ. CTXφ makes use of the chromosome dimer resolution system of V. cholerae to integrate its single stranded genome into one, the other, or both V. cholerae chromosomes. Here, we review current knowledge about this smart integration process. Medknow Publications 2011-02 /pmc/articles/PMC3089051/ /pubmed/21415494 Text en © The Indian Journal of Medical Research http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Das, Bhabatosh
Bischerour, Julien
Barre, François-Xavier
Molecular mechanism of acquisition of the cholera toxin genes
title Molecular mechanism of acquisition of the cholera toxin genes
title_full Molecular mechanism of acquisition of the cholera toxin genes
title_fullStr Molecular mechanism of acquisition of the cholera toxin genes
title_full_unstemmed Molecular mechanism of acquisition of the cholera toxin genes
title_short Molecular mechanism of acquisition of the cholera toxin genes
title_sort molecular mechanism of acquisition of the cholera toxin genes
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089051/
https://www.ncbi.nlm.nih.gov/pubmed/21415494
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