(1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione

In the isoquinoline ring system of the title compound, C(19)H(22)N(2)O(5), the N-heterocyclic ring is in a half-chair conformation. The dioxa-2-aza­spiro ring is essentially planar [maximum deviation of 0.025 (1) Å] and forms a dihedral angle of 23.51 (5)° with the benzene ring. In the crystal, mol­...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Quah, Ching Kheng, Huang, Chengmei, Yu, Haitao
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089195/
https://www.ncbi.nlm.nih.gov/pubmed/21754557
http://dx.doi.org/10.1107/S1600536811015327
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author Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
author_facet Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
author_sort Fun, Hoong-Kun
collection PubMed
description In the isoquinoline ring system of the title compound, C(19)H(22)N(2)O(5), the N-heterocyclic ring is in a half-chair conformation. The dioxa-2-aza­spiro ring is essentially planar [maximum deviation of 0.025 (1) Å] and forms a dihedral angle of 23.51 (5)° with the benzene ring. In the crystal, mol­ecules are linked via weak inter­molecular C—H⋯O and C—H⋯N hydrogen bonds into chains along [010].
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spelling pubmed-30891952011-07-13 (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione Fun, Hoong-Kun Quah, Ching Kheng Huang, Chengmei Yu, Haitao Acta Crystallogr Sect E Struct Rep Online Organic Papers In the isoquinoline ring system of the title compound, C(19)H(22)N(2)O(5), the N-heterocyclic ring is in a half-chair conformation. The dioxa-2-aza­spiro ring is essentially planar [maximum deviation of 0.025 (1) Å] and forms a dihedral angle of 23.51 (5)° with the benzene ring. In the crystal, mol­ecules are linked via weak inter­molecular C—H⋯O and C—H⋯N hydrogen bonds into chains along [010]. International Union of Crystallography 2011-04-29 /pmc/articles/PMC3089195/ /pubmed/21754557 http://dx.doi.org/10.1107/S1600536811015327 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
(1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title_full (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title_fullStr (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title_full_unstemmed (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title_short (1S*,4′S*,5R*)-1-Isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione
title_sort (1s*,4′s*,5r*)-1-isobutyl-5-meth­oxy-2′,3-dimethyl-4,6-dioxa-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′h,4′h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089195/
https://www.ncbi.nlm.nih.gov/pubmed/21754557
http://dx.doi.org/10.1107/S1600536811015327
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