9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione

The dihydro­pyridine ring in the title compound, C(26)H(32)BrNO(4), adopts an envelope conformation with the methine C atom representing the flap. The cyclo­hexenone rings also adopt envelope conformations. The phenolic hy­droxy group forms an intra­molecular hydrogen bond to one of the two keto O a...

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Detalles Bibliográficos
Autores principales: Khalilov, Ali N., Abdelhamid, Antar A., Gurbanov, Atash V., Ng, Seik Weng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089333/
https://www.ncbi.nlm.nih.gov/pubmed/21754454
http://dx.doi.org/10.1107/S1600536811013481
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author Khalilov, Ali N.
Abdelhamid, Antar A.
Gurbanov, Atash V.
Ng, Seik Weng
author_facet Khalilov, Ali N.
Abdelhamid, Antar A.
Gurbanov, Atash V.
Ng, Seik Weng
author_sort Khalilov, Ali N.
collection PubMed
description The dihydro­pyridine ring in the title compound, C(26)H(32)BrNO(4), adopts an envelope conformation with the methine C atom representing the flap. The cyclo­hexenone rings also adopt envelope conformations. The phenolic hy­droxy group forms an intra­molecular hydrogen bond to one of the two keto O atoms. Inter­molecular weak C—H⋯O hydrogen bonding is present in the crystal structure. The hy­droxy­propyl group is disordered over two sets of sites with an occupancy ratio of 0.636 (6):0.364 (6).
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spelling pubmed-30893332011-07-13 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione Khalilov, Ali N. Abdelhamid, Antar A. Gurbanov, Atash V. Ng, Seik Weng Acta Crystallogr Sect E Struct Rep Online Organic Papers The dihydro­pyridine ring in the title compound, C(26)H(32)BrNO(4), adopts an envelope conformation with the methine C atom representing the flap. The cyclo­hexenone rings also adopt envelope conformations. The phenolic hy­droxy group forms an intra­molecular hydrogen bond to one of the two keto O atoms. Inter­molecular weak C—H⋯O hydrogen bonding is present in the crystal structure. The hy­droxy­propyl group is disordered over two sets of sites with an occupancy ratio of 0.636 (6):0.364 (6). International Union of Crystallography 2011-04-16 /pmc/articles/PMC3089333/ /pubmed/21754454 http://dx.doi.org/10.1107/S1600536811013481 Text en © Khalilov et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Khalilov, Ali N.
Abdelhamid, Antar A.
Gurbanov, Atash V.
Ng, Seik Weng
9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title_full 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title_fullStr 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title_full_unstemmed 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title_short 9-(5-Bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
title_sort 9-(5-bromo-2-hy­droxy­phen­yl)-10-(2-hy­droxy­prop­yl)-3,3,6,6-tetra­methyl-1,2,3,4,5,6,7,8,9,10-deca­hydro­acridine-1,8-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089333/
https://www.ncbi.nlm.nih.gov/pubmed/21754454
http://dx.doi.org/10.1107/S1600536811013481
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