Cargando…

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts

Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete. We present here a transcriptome-wide characterization of intraerythrocytic splicing events, as captured by R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sorber, Katherine, Dimon, Michelle T., DeRisi, Joseph L.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089446/ https://www.ncbi.nlm.nih.gov/pubmed/21245033 http://dx.doi.org/10.1093/nar/gkq1223

Ejemplares similares

HMMSplicer: A Tool for Efficient and Sensitive Discovery of Known and Novel Splice Junctions in RNA-Seq Data
por: Dimon, Michelle T., et al.
Publicado: (2010)

Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans
por: Barberan-Soler, Sergio, et al.
Publicado: (2011)

Rbm20 regulates titin alternative splicing as a splicing repressor
por: Li, Shijun, et al.
Publicado: (2013)

Alternative splicing at GYNNGY 5′ splice sites: more noise, less regulation
por: Wang, Meng, et al.
Publicado: (2014)

U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing
por: Fukumura, Kazuhiro, et al.
Publicado: (2009)

Alternative splicing of CD200 is regulated by an exonic splicing enhancer and SF2/ASF
por: Chen, Zhiqi, et al.
Publicado: (2010)

The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
por: Llorian, Miriam, et al.
Publicado: (2016)

A novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites’ proliferation in human erythrocytes
por: Eshar, Shiri, et al.
Publicado: (2012)

Overlapping splicing regulatory motifs—combinatorial effects on splicing
por: Goren, Amir, et al.
Publicado: (2010)

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage
por: Comiskey, Daniel F., et al.
Publicado: (2015)

Targeting alternative splicing by RNAi: from the differential impact on splice variants to triggering artificial pre-mRNA splicing
por: Fuchs, Armin, et al.
Publicado: (2021)

Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation
por: Zhou, Xuexia, et al.
Publicado: (2014)

Different levels of alternative splicing among eukaryotes
por: Kim, Eddo, et al.
Publicado: (2007)

Cytoplasmic Drosha activity generated by alternative splicing
por: Dai, Lisheng, et al.
Publicado: (2016)

Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing
por: Peacey, Eleanor, et al.
Publicado: (2012)

Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy
por: Wojtkowiak-Szlachcic, Agnieszka, et al.
Publicado: (2015)

Splicing proofreading at 5′ splice sites by ATPase Prp28p
por: Yang, Fei, et al.
Publicado: (2013)

Global regulation of alternative splicing during myogenic differentiation
por: Bland, Christopher S., et al.
Publicado: (2010)

The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana
por: Raczynska, Katarzyna Dorota, et al.
Publicado: (2014)

Widespread alternative and aberrant splicing revealed by lariat sequencing
por: Stepankiw, Nicholas, et al.
Publicado: (2015)

Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing
por: Corioni, Margherita, et al.
Publicado: (2011)

A serine–arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii
por: Yeoh, Lee M., et al.
Publicado: (2015)

Self-splicing of a group IIC intron: 5′ exon recognition and alternative 5′ splicing events implicate the stem–loop motif of a transcriptional terminator
por: Toor, Navtej, et al.
Publicado: (2006)

SOX9 has distinct regulatory roles in alternative splicing and transcription
por: Girardot, Michael, et al.
Publicado: (2018)

Modulation of alternative splicing by long-range RNA structures in Drosophila
por: Raker, Veronica A., et al.
Publicado: (2009)

CAG repeats mimic CUG repeats in the misregulation of alternative splicing
por: Mykowska, Agnieszka, et al.
Publicado: (2011)

Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing
por: Liu, Jing, et al.
Publicado: (2012)

Alternative splicing of CNOT7 diversifies CCR4–NOT functions
por: Chapat, Clément, et al.
Publicado: (2017)

The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing
por: Sciabica, Kathryn S., et al.
Publicado: (2006)

An Alu-derived intronic splicing enhancer facilitates intronic processing and modulates aberrant splicing in ATM
por: Pastor, Tibor, et al.
Publicado: (2009)

An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly
por: Philippe, Lucas, et al.
Publicado: (2017)

Phosphorylation of the smooth muscle master splicing regulator RBPMS regulates its splicing activity
por: Barnhart, Michael D, et al.
Publicado: (2022)

In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5′ splice sites
por: Sahashi, Kentaro, et al.
Publicado: (2007)

Splicing-coupled 3′ end formation requires a terminal splice acceptor site, but not intron excision
por: Davidson, Lee, et al.
Publicado: (2013)

Modeling splicing outcome by combining 5′ss strength and splicing regulatory elements
por: Müller, Lisa, et al.
Publicado: (2022)

A G-tract element in apoptotic agents-induced alternative splicing
por: Hai, Yan, et al.
Publicado: (2008)

Alternative splicing and bioinformatic analysis of human U12-type introns
por: Chang, Wen-Cheng, et al.
Publicado: (2007)

AG-dependent 3′-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon
por: Fu, Yuan, et al.
Publicado: (2011)

Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12
por: Haque, Ariful, et al.
Publicado: (2010)

Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors
por: Culler, Stephanie J., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_3ffe4c7hr8oj9g3mtr2t1i68jk