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Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity
To explore the possibility of using restriction enzymes in a synthetic biology based on artificially expanded genetic information systems (AEGIS), 24 type-II restriction endonucleases (REases) were challenged to digest DNA duplexes containing recognition sites where individual Cs and Gs were replace...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089450/ https://www.ncbi.nlm.nih.gov/pubmed/21245035 http://dx.doi.org/10.1093/nar/gkq1274 |