Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity

To explore the possibility of using restriction enzymes in a synthetic biology based on artificially expanded genetic information systems (AEGIS), 24 type-II restriction endonucleases (REases) were challenged to digest DNA duplexes containing recognition sites where individual Cs and Gs were replace...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Yang, Zunyi, Yan, Maocai, Alvarado, J. Brian, Wang, Ganggang, Benner, Steven A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089450/
https://www.ncbi.nlm.nih.gov/pubmed/21245035
http://dx.doi.org/10.1093/nar/gkq1274

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