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Efficient Chemotherapy of Rat Glioblastoma Using Doxorubicin-Loaded PLGA Nanoparticles with Different Stabilizers

BACKGROUND: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain. For an efficient treatment of glioblastomas it is necessary to deliver anti-cancer drugs across the intact BBB. Poly(lactic-co-glycolic acid) (PLG...

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Detalles Bibliográficos
Autores principales:	Wohlfart, Stefanie, Khalansky, Alexander S., Gelperina, Svetlana, Maksimenko, Olga, Bernreuther, Christian, Glatzel, Markus, Kreuter, Jörg
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089596/ https://www.ncbi.nlm.nih.gov/pubmed/21573151 http://dx.doi.org/10.1371/journal.pone.0019121

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