Cargando…

Schistosome Infection Intensity Is Inversely Related to Auto-Reactive Antibody Levels

In animal experimental models, parasitic helminth infections can protect the host from auto-immune diseases. We conducted a population-scale human study investigating the relationship between helminth parasitism and auto-reactive antibodies and the subsequent effect of anti-helminthic treatment on t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mutapi, Francisca, Imai, Natsuko, Nausch, Norman, Bourke, Claire D., Rujeni, Nadine, Mitchell, Kate M., Midzi, Nicholas, Woolhouse, Mark E. J., Maizels, Rick M., Mduluza, Takafira
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089602/ https://www.ncbi.nlm.nih.gov/pubmed/21573157 http://dx.doi.org/10.1371/journal.pone.0019149

Ejemplares similares

Atopy Is Inversely Related to Schistosome Infection Intensity: A Comparative Study in Zimbabwean Villages with Distinct Levels of Schistosoma haematobium Infection
por: Rujeni, Nadine, et al.
Publicado: (2012)

Cytokine Responses to the Anti-schistosome Vaccine Candidate Antigen Glutathione-S-transferase Vary with Host Age and Are Boosted by Praziquantel Treatment
por: Bourke, Claire D., et al.
Publicado: (2014)

CD16 Expression on Monocytes in Healthy Individuals but Not Schistosome-Infected Patients Is Positively Associated with Levels of Parasite-Specific IgG and IgG1
por: Appleby, Laura J., et al.
Publicado: (2014)

Schistosoma haematobium Treatment in 1–5 Year Old Children: Safety and Efficacy of the Antihelminthic Drug Praziquantel
por: Mutapi, Francisca, et al.
Publicado: (2011)

Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection
por: Rujeni, Nadine, et al.
Publicado: (2013)

Association between Micronutrients (Vitamin A, D, Iron) and Schistosome-Specific Cytokine Responses in Zimbabweans Exposed to Schistosoma haematobium
por: Reilly, Liam, et al.
Publicado: (2012)

Soluble CD23 Levels are Inversely Associated with Atopy and Parasite-Specific IgE Levels but Not with Polyclonal IgE Levels in People Exposed to Helminth Infection
por: Rujeni, Nadine, et al.
Publicado: (2013)

Regulatory and Activated T Cells in Human Schistosoma haematobium Infections
por: Nausch, Norman, et al.
Publicado: (2011)

Integrated Analysis of Innate, Th1, Th2, Th17, and Regulatory Cytokines Identifies Changes in Immune Polarisation Following Treatment of Human Schistosomiasis
por: Bourke, Claire D., et al.
Publicado: (2013)

Chitinase 3-Like 1 Protein Levels Are Elevated in Schistosoma haematobium Infected Children
por: Appleby, Laura J., et al.
Publicado: (2012)

Schistosoma haematobium infection levels determine the effect of praziquantel treatment on anti-schistosome and anti-mite antibodies
por: RUJENI, N, et al.
Publicado: (2012)

Proportions of CD4+ memory T cells are altered in individuals chronically infected with Schistosoma haematobium
por: Nausch, Norman, et al.
Publicado: (2012)

Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria
por: IMAI, NATSUKO, et al.
Publicado: (2011)

Identifying and Evaluating Field Indicators of Urogenital Schistosomiasis-Related Morbidity in Preschool-Aged Children
por: Wami, Welcome M., et al.
Publicado: (2015)

Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children
por: Wami, Welcome M., et al.
Publicado: (2016)

Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: Impact on schistosome infection and cytokine levels
por: Hanton, Andrew John, et al.
Publicado: (2022)

Comparing parasitological vs serological determination of Schistosoma haematobium infection prevalence in preschool and primary school-aged children: implications for control programmes
por: WAMI, WELCOME M., et al.
Publicado: (2014)

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-γ, IL-4, IL-5 and IL-10 with age
por: Mutapi, Francisca, et al.
Publicado: (2007)

Field evaluation of a new antibody-based diagnostic for Schistosoma haematobium and S. mansoni at the point-of-care in northeast Zimbabwe
por: Nausch, Norman, et al.
Publicado: (2014)

Sources of heterogeneity in human monocyte subsets
por: Appleby, Laura J., et al.
Publicado: (2013)

Group 2 Innate Lymphoid Cell Proportions Are Diminished in Young Helminth Infected Children and Restored by Curative Anti-helminthic Treatment
por: Nausch, Norman, et al.
Publicado: (2015)

Human Schistosome Infection and Allergic Sensitisation
por: Rujeni, Nadine, et al.
Publicado: (2012)

Predicted Impact of Mass Drug Administration on the Development of Protective Immunity against Schistosoma haematobium
por: Mitchell, Kate M., et al.
Publicado: (2014)

Down Regulation of the TCR Complex CD3ζ-Chain on CD3+ T Cells: A Potential Mechanism for Helminth-Mediated Immune Modulation
por: Appleby, Laura J., et al.
Publicado: (2015)

Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden
por: Mutapi, Francisca, et al.
Publicado: (2006)

Circulating cytokine levels and antibody responses to human Schistosoma haematobium: IL-5 and IL-10 levels depend upon age and infection status
por: Milner, T, et al.
Publicado: (2010)

Investigating a strategy for quantifying schistosome infection levels in preschool-aged children using prevalence data from school-aged children
por: Lim, Rivka M., et al.
Publicado: (2020)

Age-Related Patterns in Human Myeloid Dendritic Cell Populations in People Exposed to Schistosoma haematobium Infection
por: Nausch, Norman, et al.
Publicado: (2012)

Dynamics of paediatric urogenital schistosome infection, morbidity and treatment: a longitudinal study among preschool children in Zimbabwe
por: Osakunor, Derick Nii Mensah, et al.
Publicado: (2018)

Multiplex peptide microarray profiling of antibody reactivity against neglected tropical diseases derived B-cell epitopes for serodiagnosis in Zimbabwe
por: Vengesai, Arthur, et al.
Publicado: (2022)

Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children
por: Kay, Gemma Louise, et al.
Publicado: (2015)

Seroepidemiology of Plasmodium species infections in Zimbabwean population
por: Amanfo, Seth A., et al.
Publicado: (2016)

Putting the treatment of paediatric schistosomiasis into context
por: Mduluza, Takafira, et al.
Publicado: (2017)

Population level changes in schistosome‐specific antibody levels following chemotherapy
por: Fukushige, Mizuho, et al.
Publicado: (2018)

Peptide microarray IgM and IgG screening of pre-SARS-CoV-2 human serum samples from Zimbabwe for reactivity with peptides from all seven human coronaviruses: a cross-sectional study
por: Ashworth, Jordan, et al.
Publicado: (2023)

Assessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the Griffiths Scales of Child Development
por: Mutapi, Francisca, et al.
Publicado: (2021)

Impact of Schistosome Infection on Plasmodium falciparum Malariometric Indices and Immune Correlates in School Age Children in Burma Valley, Zimbabwe
por: Sangweme, Davison T., et al.
Publicado: (2010)

Pharmacogenetics of Praziquantel Metabolism: Evaluating the Cytochrome P450 Genes of Zimbabwean Patients During a Schistosomiasis Treatment
por: Zdesenko, Grace, et al.
Publicado: (2022)

Fungal allergic sensitisation in young rural Zimbabwean children: Gut mycobiome and seroreactivity characteristics
por: Pfavayi, Lorraine Tsitsi, et al.
Publicado: (2021)

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4
por: MUTAPI, F, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_cdukippn3io9rigf6qrm3tulck