Cargando…
HSV Neutralization by the Microbicidal Candidate C5A
Genital herpes is a major risk factor in acquiring human immunodeficiency virus type-1 (HIV-1) infection and is caused by both Herpes Simplex virus type 1 (HSV-1) and HSV-2. The amphipathic peptide C5A, derived from the non-structural hepatitis C virus (HCV) protein 5A, was shown to prevent HIV-1 in...
Autores principales: | de Witte, Lot, Bobardt, Michael D., Chatterji, Udayan, van Loenen, Freek B., Verjans, Georges M. G. M., Geijtenbeek, Teunis B. H., Gallay, Philippe A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089603/ https://www.ncbi.nlm.nih.gov/pubmed/21573158 http://dx.doi.org/10.1371/journal.pone.0018917 |
Ejemplares similares
-
Both Cyclophilin Inhibitors and Direct-Acting Antivirals Prevent PKR Activation in HCV-Infected Cells
por: Bobardt, Michael, et al.
Publicado: (2014) -
The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
por: Bobardt, Michael, et al.
Publicado: (2019) -
Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection
por: Chatterji, Udayan, et al.
Publicado: (2016) -
HCV Core Residues Critical for Infectivity Are Also Involved in Core-NS5A Complex Formation
por: Gawlik, Katarzyna, et al.
Publicado: (2014) -
The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice
por: Bobardt, Michael, et al.
Publicado: (2020)