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Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial Cells
BACKGROUND: Formation of apical compartments underlies the morphogenesis of most epithelial organs during development. The extracellular matrix (ECM), particularly the basement membrane (BM), plays an important role in orienting the apico-basal polarity and thereby the positioning of apical lumens....
Autores principales: | Myllymäki, Satu Marja, Teräväinen, Terhi Piritta, Manninen, Aki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089628/ https://www.ncbi.nlm.nih.gov/pubmed/21573123 http://dx.doi.org/10.1371/journal.pone.0019453 |
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