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Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells

MITOSTATIN, a novel putative tumor suppressor gene induced by decorin overexpression, is expressed in most normal human tissues but is markedly down-regulated in advanced stages of mammary and bladder carcinomas. Mitostatin negatively affects cell growth, induces cell death and regulates the express...

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Detalles Bibliográficos
Autores principales: Fassan, Matteo, D'Arca, Domenico, Letko, Juraj, Vecchione, Andrea, Gardiman, Marina P., McCue, Peter, Wildemore, Bernadette, Rugge, Massimo, Shupp-Byrne, Dolores, Gomella, Leonard G., Morrione, Andrea, Iozzo, Renato V., Baffa, Raffaele
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089640/
https://www.ncbi.nlm.nih.gov/pubmed/21573075
http://dx.doi.org/10.1371/journal.pone.0019771