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Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis
Advances in high-performance computing are enabling a new generation of software tools that employ computational modeling for surgical planning. Surgical management of laryngeal paralysis is one area where such computational tools could have a significant impact. The current paper describes a compre...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089877/ https://www.ncbi.nlm.nih.gov/pubmed/21556320 http://dx.doi.org/10.3389/fphys.2011.00019 |
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author | Mittal, Rajat Zheng, Xudong Bhardwaj, Rajneesh Seo, Jung Hee Xue, Qian Bielamowicz, Steven |
author_facet | Mittal, Rajat Zheng, Xudong Bhardwaj, Rajneesh Seo, Jung Hee Xue, Qian Bielamowicz, Steven |
author_sort | Mittal, Rajat |
collection | PubMed |
description | Advances in high-performance computing are enabling a new generation of software tools that employ computational modeling for surgical planning. Surgical management of laryngeal paralysis is one area where such computational tools could have a significant impact. The current paper describes a comprehensive effort to develop a software tool for planning medialization laryngoplasty where a prosthetic implant is inserted into the larynx in order to medialize the paralyzed vocal fold (VF). While this is one of the most common procedures used to restore voice in patients with VF paralysis, it has a relatively high revision rate, and the tool being developed is expected to improve surgical outcomes. This software tool models the biomechanics of airflow-induced vibration in the human larynx and incorporates sophisticated approaches for modeling the turbulent laryngeal flow, the complex dynamics of the VFs, as well as the production of voiced sound. The current paper describes the key elements of the modeling approach, presents computational results that demonstrate the utility of the approach and also describes some of the limitations and challenges. |
format | Text |
id | pubmed-3089877 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-30898772011-05-09 Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis Mittal, Rajat Zheng, Xudong Bhardwaj, Rajneesh Seo, Jung Hee Xue, Qian Bielamowicz, Steven Front Physiol Physiology Advances in high-performance computing are enabling a new generation of software tools that employ computational modeling for surgical planning. Surgical management of laryngeal paralysis is one area where such computational tools could have a significant impact. The current paper describes a comprehensive effort to develop a software tool for planning medialization laryngoplasty where a prosthetic implant is inserted into the larynx in order to medialize the paralyzed vocal fold (VF). While this is one of the most common procedures used to restore voice in patients with VF paralysis, it has a relatively high revision rate, and the tool being developed is expected to improve surgical outcomes. This software tool models the biomechanics of airflow-induced vibration in the human larynx and incorporates sophisticated approaches for modeling the turbulent laryngeal flow, the complex dynamics of the VFs, as well as the production of voiced sound. The current paper describes the key elements of the modeling approach, presents computational results that demonstrate the utility of the approach and also describes some of the limitations and challenges. Frontiers Research Foundation 2011-05-02 /pmc/articles/PMC3089877/ /pubmed/21556320 http://dx.doi.org/10.3389/fphys.2011.00019 Text en Copyright © 2011 Mittal, Zheng, Bhardwaj, Seo, Xue and Bielamowicz. http://www.frontiersin.org/licenseagreement This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with. |
spellingShingle | Physiology Mittal, Rajat Zheng, Xudong Bhardwaj, Rajneesh Seo, Jung Hee Xue, Qian Bielamowicz, Steven Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title | Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title_full | Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title_fullStr | Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title_full_unstemmed | Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title_short | Toward A Simulation-Based Tool for the Treatment of Vocal Fold Paralysis |
title_sort | toward a simulation-based tool for the treatment of vocal fold paralysis |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089877/ https://www.ncbi.nlm.nih.gov/pubmed/21556320 http://dx.doi.org/10.3389/fphys.2011.00019 |
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