MTB-PCDB: Mycobacterium tuberculosis proteome comparison database

The Mycobacterium tuberculosis Proteome Comparison Database (MTB-PCDB) is an online database providing integrated access to proteome sequence comparison data for five strains of Mycobacterium tuberculosis (H37Rv, H37Ra, CDC 1551, F11 and KZN 1435) sequenced completely so far. MTB-PCDB currently host...

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Autores principales: Jena, Lingaraja, Wankhade, Gauri, Kumar, Satish, Harinath, Bhaskar Chinnaiah
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089889/
https://www.ncbi.nlm.nih.gov/pubmed/21584191
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author Jena, Lingaraja
Wankhade, Gauri
Kumar, Satish
Harinath, Bhaskar Chinnaiah
author_facet Jena, Lingaraja
Wankhade, Gauri
Kumar, Satish
Harinath, Bhaskar Chinnaiah
author_sort Jena, Lingaraja
collection PubMed
description The Mycobacterium tuberculosis Proteome Comparison Database (MTB-PCDB) is an online database providing integrated access to proteome sequence comparison data for five strains of Mycobacterium tuberculosis (H37Rv, H37Ra, CDC 1551, F11 and KZN 1435) sequenced completely so far. MTB-PCDB currently hosts 40252 protein sequence comparison data obtained through inter-strain proteome comparison of five different strains of MTB. 2373 proteins were found to be identical in all 5 strains using MTB H(37)Rv as reference strain. To enable wide use of this data, MTB-PCDB provides a set of tools for searching, browsing, analyzing and downloading the data. By bringing together, M. tuberculosis proteome comparison among virulent & avirulent strains and also drug susceptible & drug resistance strains MTB-PCDB provides a unique discovery platform for comparative proteomics among these strains which may give insights into the discovery & development of TB drugs, vaccines and biomarkers. AVAILABILITY: The database is available for free at http://www.bicjbtdrc-mgims.in/MTB-PCDB/
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spelling pubmed-30898892011-05-16 MTB-PCDB: Mycobacterium tuberculosis proteome comparison database Jena, Lingaraja Wankhade, Gauri Kumar, Satish Harinath, Bhaskar Chinnaiah Bioinformation Database The Mycobacterium tuberculosis Proteome Comparison Database (MTB-PCDB) is an online database providing integrated access to proteome sequence comparison data for five strains of Mycobacterium tuberculosis (H37Rv, H37Ra, CDC 1551, F11 and KZN 1435) sequenced completely so far. MTB-PCDB currently hosts 40252 protein sequence comparison data obtained through inter-strain proteome comparison of five different strains of MTB. 2373 proteins were found to be identical in all 5 strains using MTB H(37)Rv as reference strain. To enable wide use of this data, MTB-PCDB provides a set of tools for searching, browsing, analyzing and downloading the data. By bringing together, M. tuberculosis proteome comparison among virulent & avirulent strains and also drug susceptible & drug resistance strains MTB-PCDB provides a unique discovery platform for comparative proteomics among these strains which may give insights into the discovery & development of TB drugs, vaccines and biomarkers. AVAILABILITY: The database is available for free at http://www.bicjbtdrc-mgims.in/MTB-PCDB/ Biomedical Informatics 2011-04-22 /pmc/articles/PMC3089889/ /pubmed/21584191 Text en © 2011 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Database
Jena, Lingaraja
Wankhade, Gauri
Kumar, Satish
Harinath, Bhaskar Chinnaiah
MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title_full MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title_fullStr MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title_full_unstemmed MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title_short MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
title_sort mtb-pcdb: mycobacterium tuberculosis proteome comparison database
topic Database
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089889/
https://www.ncbi.nlm.nih.gov/pubmed/21584191
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AT harinathbhaskarchinnaiah mtbpcdbmycobacteriumtuberculosisproteomecomparisondatabase

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