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Pharmacologic modulation of experimentally induced allergic asthma

Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of su...

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Detalles Bibliográficos
Autores principales: Fraňová, Soňa, Strapková, Anna, Mokrý, Juraj, Šutovská, Martina, Jošková, Marta, Sadloňová, Vladimíra, Antošová, Martina, Pavelčíková, Darina, Flešková, Dana, Nosáĺová, Gabriela
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090051/
https://www.ncbi.nlm.nih.gov/pubmed/21577281
http://dx.doi.org/10.2478/v10102-011-0006-x
Descripción
Sumario:Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of substances able to influence activities of ion channels, phosphodiesterase (PDE) isoforms, substances from the group of polyphenols and NO metabolism modulators during experimentally induced allergic asthma.