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Non-erythropoietic erythropoietin derivatives protect from light-induced and genetic photoreceptor degeneration

Given the high genetic heterogeneity of inherited retinal degenerations (IRDs), a wide applicable treatment would be desirable to halt/slow progressive photoreceptor (PR) cell loss in a mutation-independent manner. In addition to its erythropoietic activity, erythropoietin (EPO) presents neurotrophi...

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Detalles Bibliográficos
Autores principales: Colella, Pasqualina, Iodice, Carolina, Di Vicino, Umberto, Annunziata, Ida, Surace, Enrico M., Auricchio, Alberto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090200/
https://www.ncbi.nlm.nih.gov/pubmed/21421996
http://dx.doi.org/10.1093/hmg/ddr115