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An NFKB1 Promoter Insertion/Deletion Polymorphism Influences Risk and Outcome in Acute Respiratory Distress Syndrome among Caucasians
BACKGROUND: Nuclear factor-κB (NF-κB) is required for transcription of many pro-inflammatory genes and has been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We hypothesized that a known functional polymorphism in the promoter of the NFKB1 gene may affect susceptibili...
Autores principales: | Bajwa, Ednan K., Cremer, Paul C., Gong, Michelle N., Zhai, Rihong, Su, Li, Thompson, B. Taylor, Christiani, David C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090449/ https://www.ncbi.nlm.nih.gov/pubmed/21573030 http://dx.doi.org/10.1371/journal.pone.0019469 |
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