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Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult
Visceral leishmaniasis is characterized by fever, cachexia, hepatosplenomegaly, pancytopenia, and hypergammaglobulinemia. Cough may be a presenting symptom as well. However, pulmonary involvement is considered rare and mainly described in immunocompromised patients. We describe a case of an immunoco...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090634/ https://www.ncbi.nlm.nih.gov/pubmed/21577261 http://dx.doi.org/10.1155/2011/561985 |
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author | Kotsifas, Konstantinos Metaxas, Eugenios Koutsouvelis, Ioannis Skoutelis, Athanassios Kara, Panayiota Tatsis, George |
author_facet | Kotsifas, Konstantinos Metaxas, Eugenios Koutsouvelis, Ioannis Skoutelis, Athanassios Kara, Panayiota Tatsis, George |
author_sort | Kotsifas, Konstantinos |
collection | PubMed |
description | Visceral leishmaniasis is characterized by fever, cachexia, hepatosplenomegaly, pancytopenia, and hypergammaglobulinemia. Cough may be a presenting symptom as well. However, pulmonary involvement is considered rare and mainly described in immunocompromised patients. We describe a case of an immunocompetent adult whose clinical presentation was dominated by cough and hemoptysis. Bronchoscopy revealed a discreet polypoid mucosal endobronchial lesion whose biopsy yielded Leishmania amastigotes within histiocytes. Transbronchial needle biopsy of a right paratracheal lymph node was also positive. Leishmania amastigotes were also found on bone marrow and liver biopsies. Treatment with IV Amphotericin B was successful. In conclusion, cough should not be overlooked as a presenting symptom of visceral leishmaniasis and may be a sign of pulmonary involvement. |
format | Text |
id | pubmed-3090634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-30906342011-05-16 Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult Kotsifas, Konstantinos Metaxas, Eugenios Koutsouvelis, Ioannis Skoutelis, Athanassios Kara, Panayiota Tatsis, George Case Rep Med Case Report Visceral leishmaniasis is characterized by fever, cachexia, hepatosplenomegaly, pancytopenia, and hypergammaglobulinemia. Cough may be a presenting symptom as well. However, pulmonary involvement is considered rare and mainly described in immunocompromised patients. We describe a case of an immunocompetent adult whose clinical presentation was dominated by cough and hemoptysis. Bronchoscopy revealed a discreet polypoid mucosal endobronchial lesion whose biopsy yielded Leishmania amastigotes within histiocytes. Transbronchial needle biopsy of a right paratracheal lymph node was also positive. Leishmania amastigotes were also found on bone marrow and liver biopsies. Treatment with IV Amphotericin B was successful. In conclusion, cough should not be overlooked as a presenting symptom of visceral leishmaniasis and may be a sign of pulmonary involvement. Hindawi Publishing Corporation 2011 2011-03-10 /pmc/articles/PMC3090634/ /pubmed/21577261 http://dx.doi.org/10.1155/2011/561985 Text en Copyright © 2011 Konstantinos Kotsifas et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kotsifas, Konstantinos Metaxas, Eugenios Koutsouvelis, Ioannis Skoutelis, Athanassios Kara, Panayiota Tatsis, George Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title | Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title_full | Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title_fullStr | Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title_full_unstemmed | Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title_short | Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult |
title_sort | visceral leishmaniasis with endobronchial involvement in an immunocompetent adult |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090634/ https://www.ncbi.nlm.nih.gov/pubmed/21577261 http://dx.doi.org/10.1155/2011/561985 |
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