Cargando…

Hypermethylation of CCND2 May Reflect a Smoking-Induced Precancerous Change in the Lung

It remains unknown whether tobacco smoke induces DNA hypermethylation as an early event in carcinogenesis or as a late event, specific to overt cancer tissue. Using MethyLight assays, we analyzed 316 lung tissue samples from 151 cancer-free subjects (121 ever-smokers and 30 never-smokers) for hyperm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salskov, Alexander, Hawes, Stephen E., Stern, Joshua E., Feng, Qinghua, Jordan, C. Diana, Wiens, Linda, Rasey, Janet, Lu, Hiep, Kiviat, Nancy B., Vesselle, Hubert
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090638/ https://www.ncbi.nlm.nih.gov/pubmed/21577262 http://dx.doi.org/10.1155/2011/950140

Ejemplares similares

Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target
por: Hung, Chin-Sheng, et al.
Publicado: (2018)

Expression of Mir-21 and Mir-143 in Cervical Specimens Ranging from Histologically Normal through to Invasive Cervical Cancer
por: Deftereos, Georgios, et al.
Publicado: (2011)

Mutually exclusive epigenetic modification on SIX6 with hypermethylation for precancerous stage and metastasis emergence tracing
por: Dong, Shihua, et al.
Publicado: (2022)

Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions
por: Sajibu, Sija, et al.
Publicado: (2023)

MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features
por: Lee, Heejeong, et al.
Publicado: (2012)

Analysis of Tp53 Codon 72 Polymorphisms, Tp53 Mutations, and HPV Infection in Cutaneous Squamous Cell Carcinomas
por: Loeb, Keith R., et al.
Publicado: (2012)

Toxicology evaluation of radiotracer doses of 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) for human PET imaging: Laboratory analysis of serial blood samples and comparison to previously investigated therapeutic FLT doses
por: Turcotte, Eric, et al.
Publicado: (2007)

pncCCND1_B Engages an Inhibitory Protein Network to Downregulate CCND1 Expression upon DNA Damage
por: Palombo, Ramona, et al.
Publicado: (2022)

COVID-19 in an asymptomatic patient undergoing FDG PET/CT
por: Johnson, Lisa N., et al.
Publicado: (2020)

E-cadherin promoter hypermethylation may contribute to protein inactivation in pterygia
por: Young, Chi-Hsien, et al.
Publicado: (2010)

Diffuse Reflectance Spectroscopy of the Oral Mucosa: In Vivo Experimental Validation of the Precancerous Lesions Early Detection Possibility
por: Kolpakov, Alexander V., et al.
Publicado: (2023)

Cell Cycle Regulation by Alternative Polyadenylation of CCND1
por: Wang, Qiong, et al.
Publicado: (2018)

The Silencing of CCND2 by Promoter Aberrant Methylation in Renal Cell Cancer and Analysis of the Correlation between CCND2 Methylation Status and Clinical Features
por: Wang, Lu, et al.
Publicado: (2016)

Cholecystokinin-B Receptor-Targeted Nanoparticle for Imaging and Detection of Precancerous Lesions in the Pancreas
por: Smith, Jill P., et al.
Publicado: (2021)

Detection of precancerous lesions in the oral cavity using oblique polarized reflectance spectroscopy: a clinical feasibility study
por: Bailey, Maria J., et al.
Publicado: (2017)

Techniques for Precancerous Lesion Diagnosis
por: Mendes, Sarah Freygang, et al.
Publicado: (2011)

Precancerous Lesions in Colorectal Cancer
por: Sandouk, Fayez, et al.
Publicado: (2013)

Precancerous Lesions and Carcinoma of the Pancreas
por: Hackert, Thilo, et al.
Publicado: (2015)

Precancerous Lesions and Carcinoma of the Pancreas
por: Büchler, Markus W., et al.
Publicado: (2015)

Predisposing and Precancerous Conditions of the Breast
Publicado: (1904)

Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling
por: Li, Qinghai, et al.
Publicado: (2019)

MiR-146a-5p inhibits cell proliferation and cell cycle progression in NSCLC cell lines by targeting CCND1 and CCND2
por: Li, Yan-Li, et al.
Publicado: (2016)

Semi-quantitative metabolic values on FDG PET/CT including extracardiac sites of disease as a predictor of treatment course in patients with cardiac sarcoidosis
por: Ishiyama, Mitsutomi, et al.
Publicado: (2017)

Gastric epithelial histology and precancerous conditions
por: Yang, Hang, et al.
Publicado: (2022)

IPA Analysis of Cervicovaginal Fluid from Precancerous Women Points to the Presence of Biomarkers for the Precancerous State of Cervical Carcinoma
por: Van Ostade, Xaveer, et al.
Publicado: (2014)

SOX2 promoter hypermethylation in non-smoking Taiwanese adults residing in air pollution areas
por: Tantoh, Disline Manli, et al.
Publicado: (2019)

CCND1 gene polymorphic variants in patients with differentiated thyroid carcinoma
por: HRYHOROWICZ, SZYMON, et al.
Publicado: (2015)

CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia
por: Ketzer, Franz, et al.
Publicado: (2022)

WILMS TUMOR MUTATIONAL SUBCLASSES CONVERGE TO DRIVE CCND2 OVEREXPRESSION
por: Xu, Lin, et al.
Publicado: (2023)

CCND1 Overexpression in Idiopathic Dilated Cardiomyopathy: A Promising Biomarker?
por: Dehghani, Khatereh, et al.
Publicado: (2023)

Anaplastic multiple myeloma with amplification of the IGH-CCND1 gene fusion
por: Alencar, Rafael Nobrega, et al.
Publicado: (2023)

Detection of p53 mutations in precancerous gastric tissue
por: Morgan, C, et al.
Publicado: (2003)

Hypermethylation of the TSPOAP1-AS1 Promoter May Be Associated with Obesity in Overweight/Obese Korean Subjects
por: Yim, Nam-Hui, et al.
Publicado: (2020)

Pathology of Senegalese breast cancers
por: Fitzpatrick, Megan Burke, et al.
Publicado: (2019)

A matched prospective study of human immunodeficiency virus serostatus, human papillomavirus DNA, and cervical lesions detected by cytology and colposcopy.
por: Eckert, L O, et al.
Publicado: (1999)

Short Telomere Lesions with Dysplastic Metaplasia Histology May Represent Precancerous Lesions of Helicobacter pylori-Positive Gastric Mucosa
por: Fujiwara-Tani, Rina, et al.
Publicado: (2023)

Rapid construction of a dendritic cell vaccine through physical perturbation and apoptotic malignant T cell loading
por: Salskov-Iversen, Maria, et al.
Publicado: (2005)

Untrapped: bilateral hypoplasia of the trapezius muscle
por: Rounds, BaileaSue R., et al.
Publicado: (2023)

Clinical significance of HPV-DNA testing for precancerous cervical lesionS
por: Moarcăs, M, et al.
Publicado: (2014)

circRNA circ‐CCND1 promotes the proliferation of laryngeal squamous cell carcinoma through elevating CCND1 expression via interacting with HuR and miR‐646
por: Zang, Yanzi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1i310het1firioeqm7bcltdohj