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Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1
BACKGROUND: Neuroinflammation and nitroxidative stress are implicated in the pathophysiology of neuropathic pain. In view of both processes, microglial and astroglial activation in the spinal dorsal horn play a predominant role. The present study investigated the severity of neuropathic pain and the...
Autores principales: | Berger, Julie V, Deumens, Ronald, Goursaud, Stéphanie, Schäfer, Sabrina, Lavand'homme, Patricia, Joosten, Elbert A, Hermans, Emmanuel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090736/ https://www.ncbi.nlm.nih.gov/pubmed/21489258 http://dx.doi.org/10.1186/1742-2094-8-33 |
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