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Molecular Basis for Transmission Barrier and Interference between Closely Related Prion Proteins in Yeast

Replicating amyloids, called prions, are responsible for transmissible neurodegenerative diseases in mammals and some heritable phenotypes in fungi. The transmission of prions between species is usually inhibited, being highly sensitive to small differences in amino acid sequence of the prion-formin...

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Detalles Bibliográficos
Autores principales: Afanasieva, Evgenia G., Kushnirov, Vitaly V., Tuite, Mick F., Ter-Avanesyan, Michael D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091186/
https://www.ncbi.nlm.nih.gov/pubmed/21454674
http://dx.doi.org/10.1074/jbc.M110.183889