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Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor

The determinants of single channel conductance (γ) and ion selectivity within eukaryotic pentameric ligand-gated ion channels have traditionally been ascribed to amino acid residues within the second transmembrane domain and flanking sequences of their component subunits. However, recent evidence su...

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Detalles Bibliográficos
Autores principales:	Livesey, Matthew R., Cooper, Michelle A., Lambert, Jeremy J., Peters, John A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091210/ https://www.ncbi.nlm.nih.gov/pubmed/21454663 http://dx.doi.org/10.1074/jbc.M111.219618

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