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The Catalytic Architecture of Leukotriene C(4) Synthase with Two Arginine Residues

Leukotriene (LT) C(4) and its metabolites, LTD(4) and LTE(4), are involved in the pathobiology of bronchial asthma. LTC(4) synthase is the nuclear membrane-embedded enzyme responsible for LTC(4) biosynthesis, catalyzing the conjugation of two substrates that have considerably different water solubil...

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Detalles Bibliográficos
Autores principales:	Saino, Hiromichi, Ukita, Yoko, Ago, Hideo, Irikura, Daisuke, Nisawa, Atsushi, Ueno, Go, Yamamoto, Masaki, Kanaoka, Yoshihide, Lam, Bing K., Austen, K. Frank, Miyano, Masashi
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091245/ https://www.ncbi.nlm.nih.gov/pubmed/21454538 http://dx.doi.org/10.1074/jbc.M110.150177

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