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Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
BACKGROUND: Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presenc...
Autores principales: | Mahony, Shaun, Mazzoni, Esteban O, McCuine, Scott, Young, Richard A, Wichterle, Hynek, Gifford, David K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091300/ https://www.ncbi.nlm.nih.gov/pubmed/21232103 http://dx.doi.org/10.1186/gb-2011-12-1-r2 |
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