The Werner syndrome protein: linking the replication checkpoint response to genome stability

The Werner syndrome protein (WRN) is a member of the human RecQ family DNA helicases implicated in the maintenance of genome stability. Loss of WRN gives rise to the Werner syndrome, a genetic disease characterised by premature aging and cancer predisposition. WRN plays a crucial role in the respons...

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Detalles Bibliográficos
Autores principales: Pichierri, Pietro, Ammazzalorso, Francesca, Bignami, Margherita, Franchitto, Annapaola
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091524/
https://www.ncbi.nlm.nih.gov/pubmed/21389352

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