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The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

The target of rapamycin (TOR) pathway regulates cell growth and aging in various organisms. In Saccharomyces cerevisiae, silent information regulator 2 (Sir2) modulates cellular senescence. Moreover, Sir2 plays a crucial role in promoting ribosomal DNA (rDNA) stability and longevity under TOR inhibi...

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Detalles Bibliográficos
Autores principales:	Ha, Cheol Woong, Huh, Won-Ki
Formato:	Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2011
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091525/ https://www.ncbi.nlm.nih.gov/pubmed/21415463

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