Cargando…

The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids

BACKGROUND: The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship betw...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulugeta Achame, Eskeatnaf, Wassenaar, Evelyne, Hoogerbrugge, Jos W, Sleddens-Linkels, Esther, Ooms, Marja, Sun, Zu-Wen, van IJcken, Wilfred FJ, Grootegoed, J Anton, Baarends, Willy M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091626/
https://www.ncbi.nlm.nih.gov/pubmed/20537150
http://dx.doi.org/10.1186/1471-2164-11-367