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Using paired-end sequences to optimise parameters for alignment of sequence reads against related genomes
BACKGROUND: The advent of cheap high through-put sequencing methods has facilitated low coverage skims of a large number of organisms. To maximise the utility of the sequences, assembly into contigs and then ordering of those contigs is required. Whilst sequences can be assembled into contigs de nov...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091654/ https://www.ncbi.nlm.nih.gov/pubmed/20678236 http://dx.doi.org/10.1186/1471-2164-11-458 |