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Distributed probing of chromatin structure in vivo reveals pervasive chromatin accessibility for expressed and non-expressed genes during tissue differentiation in C. elegans

BACKGROUND: Tissue differentiation is accompanied by genome-wide changes in the underlying chromatin structure and dynamics, or epigenome. By controlling when, where, and what regulatory factors have access to the underlying genomic DNA, the epigenome influences the cell's transcriptome and ult...

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Detalles Bibliográficos
Autores principales: Sha, Ky, Gu, Sam G, Pantalena-Filho, Luiz C, Goh, Amy, Fleenor, Jamie, Blanchard, Daniel, Krishna, Chaya, Fire, Andrew
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091661/
https://www.ncbi.nlm.nih.gov/pubmed/20691096
http://dx.doi.org/10.1186/1471-2164-11-465