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Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation

BACKGROUND: Identifying associations between genotypes and gene expression levels using microarrays has enabled systematic interrogation of regulatory variation underlying complex phenotypes. This approach has vast potential for functional characterization of disease states, but its prohibitive cost...

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Detalles Bibliográficos
Autores principales: Babak, Tomas, Garrett-Engele, Philip, Armour, Christopher D, Raymond, Christopher K, Keller, Mark P, Chen, Ronghua, Rohl, Carol A, Johnson, Jason M, Attie, Alan D, Fraser, Hunter B, Schadt, Eric E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091669/
https://www.ncbi.nlm.nih.gov/pubmed/20707912
http://dx.doi.org/10.1186/1471-2164-11-473