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Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation
BACKGROUND: Identifying associations between genotypes and gene expression levels using microarrays has enabled systematic interrogation of regulatory variation underlying complex phenotypes. This approach has vast potential for functional characterization of disease states, but its prohibitive cost...
Autores principales: | Babak, Tomas, Garrett-Engele, Philip, Armour, Christopher D, Raymond, Christopher K, Keller, Mark P, Chen, Ronghua, Rohl, Carol A, Johnson, Jason M, Attie, Alan D, Fraser, Hunter B, Schadt, Eric E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091669/ https://www.ncbi.nlm.nih.gov/pubmed/20707912 http://dx.doi.org/10.1186/1471-2164-11-473 |
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