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Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

BACKGROUND: Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumors using the Affymetrix GeneChip Human Mapping 500K arr...

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Detalles Bibliográficos
Autores principales:	Hu, Nan, Clifford, Robert J, Yang, Howard H, Wang, Chaoyu, Goldstein, Alisa M, Ding, Ti, Taylor, Philip R, Lee, Maxwell P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091724/ https://www.ncbi.nlm.nih.gov/pubmed/20955586 http://dx.doi.org/10.1186/1471-2164-11-576

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