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Genes optimized by evolution for accurate and fast translation encode in Archaea and Bacteria a broad and characteristic spectrum of protein functions

BACKGROUND: In many microbial genomes, a strong preference for a small number of codons can be observed in genes whose products are needed by the cell in large quantities. This codon usage bias (CUB) improves translational accuracy and speed and is one of several factors optimizing cell growth. Wher...

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Detalles Bibliográficos
Autores principales: von Mandach, Conrad, Merkl, Rainer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091758/
https://www.ncbi.nlm.nih.gov/pubmed/21050470
http://dx.doi.org/10.1186/1471-2164-11-617