Cargando…

An OBSL1-Cul7(Fbxw8) Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning

The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored. Here, we report that the E3 ubiquitin ligase Cul7(Fbxw8) localizes to the Golgi c...

Descripción completa

Detalles Bibliográficos
Autores principales: Litterman, Nadia, Ikeuchi, Yoshiho, Gallardo, Gilbert, O'Connell, Brenda C., Sowa, Mathew E., Gygi, Steven P., Harper, J. Wade, Bonni, Azad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091842/
https://www.ncbi.nlm.nih.gov/pubmed/21572988
http://dx.doi.org/10.1371/journal.pbio.1001060