Insights into cancer mechanisms from genomic research on urological cancers

Molecular mechanisms driving cancer development and progression are rarely unique to one cancer type. Rather, recent genomic studies of urological cancers suggest that common mechanisms recur with variations. Examples include alterations in hypoxia response regulation, epigenetic regulator proteins,...

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Detalles Bibliográficos
Autores principales: Schulz, Wolfgang A, Ribarska, Teodora
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092105/
https://www.ncbi.nlm.nih.gov/pubmed/21457491
http://dx.doi.org/10.1186/gm234
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author Schulz, Wolfgang A
Ribarska, Teodora
author_facet Schulz, Wolfgang A
Ribarska, Teodora
author_sort Schulz, Wolfgang A
collection PubMed
description Molecular mechanisms driving cancer development and progression are rarely unique to one cancer type. Rather, recent genomic studies of urological cancers suggest that common mechanisms recur with variations. Examples include alterations in hypoxia response regulation, epigenetic regulator proteins, and signal transduction pathways in renal, prostatic and urothelial carcinomas. Consideration of these variations alongside the common basic cancer mechanisms might be important for the successful development of targeted therapies.
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spelling pubmed-30921052012-03-31 Insights into cancer mechanisms from genomic research on urological cancers Schulz, Wolfgang A Ribarska, Teodora Genome Med Research Highlight Molecular mechanisms driving cancer development and progression are rarely unique to one cancer type. Rather, recent genomic studies of urological cancers suggest that common mechanisms recur with variations. Examples include alterations in hypoxia response regulation, epigenetic regulator proteins, and signal transduction pathways in renal, prostatic and urothelial carcinomas. Consideration of these variations alongside the common basic cancer mechanisms might be important for the successful development of targeted therapies. BioMed Central 2011-03-31 /pmc/articles/PMC3092105/ /pubmed/21457491 http://dx.doi.org/10.1186/gm234 Text en Copyright ©2010 BioMed Central Ltd.
spellingShingle Research Highlight
Schulz, Wolfgang A
Ribarska, Teodora
Insights into cancer mechanisms from genomic research on urological cancers
title Insights into cancer mechanisms from genomic research on urological cancers
title_full Insights into cancer mechanisms from genomic research on urological cancers
title_fullStr Insights into cancer mechanisms from genomic research on urological cancers
title_full_unstemmed Insights into cancer mechanisms from genomic research on urological cancers
title_short Insights into cancer mechanisms from genomic research on urological cancers
title_sort insights into cancer mechanisms from genomic research on urological cancers
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092105/
https://www.ncbi.nlm.nih.gov/pubmed/21457491
http://dx.doi.org/10.1186/gm234
work_keys_str_mv AT schulzwolfganga insightsintocancermechanismsfromgenomicresearchonurologicalcancers
AT ribarskateodora insightsintocancermechanismsfromgenomicresearchonurologicalcancers

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