Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics

Aberrant DNA methylation, in particular promoter hypermethylation and transcriptional silencing of tumor suppressor genes, has an important role in the development of many human cancers, including renal cell carcinoma (RCC). Indeed, apart from mutations in the well studied von Hippel-Lindau gene (VH...

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Detalles Bibliográficos
Autores principales: Morris, Mark R, Maher, Eamonn R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092110/
https://www.ncbi.nlm.nih.gov/pubmed/20815920
http://dx.doi.org/10.1186/gm180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092110/
https://www.ncbi.nlm.nih.gov/pubmed/20815920
http://dx.doi.org/10.1186/gm180

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