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Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics
Aberrant DNA methylation, in particular promoter hypermethylation and transcriptional silencing of tumor suppressor genes, has an important role in the development of many human cancers, including renal cell carcinoma (RCC). Indeed, apart from mutations in the well studied von Hippel-Lindau gene (VH...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092110/ https://www.ncbi.nlm.nih.gov/pubmed/20815920 http://dx.doi.org/10.1186/gm180 |