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Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain

Neural stem cells (NSCs) in the adult mammalian brain generate neurons and glia throughout life. However, the physiological role of adult neurogenesis and the use of NSCs for therapy are highly controversial. One factor hampering the study and manipulation of neurogenesis is that NSCs, like most adu...

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Detalles Bibliográficos
Autores principales: Artegiani, Benedetta, Lindemann, Dirk, Calegari, Federico
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092341/
https://www.ncbi.nlm.nih.gov/pubmed/21482697
http://dx.doi.org/10.1084/jem.20102167