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Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion

Upon host cell contact, the protozoan parasite Trypanosoma cruzi triggers cytosolic Ca(2+) transients that induce exocytosis of lysosomes, a process required for cell invasion. However, the exact mechanism by which lysosomal exocytosis mediates T. cruzi internalization remains unclear. We show that...

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Detalles Bibliográficos
Autores principales: Fernandes, Maria Cecilia, Cortez, Mauro, Flannery, Andrew R., Tam, Christina, Mortara, Renato A., Andrews, Norma W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092353/
https://www.ncbi.nlm.nih.gov/pubmed/21536739
http://dx.doi.org/10.1084/jem.20102518